1. A prospective study in which 77 patients were treated with Invisalign, fixed braces or no treatment (Levrini et al 2015b) found that bacteria concentrations were significantly lower in the Invisalign-treated patients compared with those using fixed braces (104,536,026, 2739 and 8187 in the fixed orthodontic, the Invisalign and control groups, respectively; p<0.05).


  1. Date on file at Align Technology